anti- ERCC3 antibody

Uncover the intricacies of DNA repair and genomic stability with our Anti-ERCC3 Antibody, an essential tool for studying ERCC3, a vital component of the DNA repair machinery. With 100µg of high-quality antibody, you have the precision and reliability required for your experiments.

ERCC3 is a key player in repairing DNA damage, preventing mutations, and maintaining genomic integrity. Our antibody is rigorously tested for specificity and sensitivity, making it ideal for techniques such as immunoblotting, immunoprecipitation, and immunofluorescence.

The Anti-ERCC3 Antibody is your essential tool for exploring ERCC3's functions with precision, contributing to a deeper understanding of DNA repair and genome maintenance. Whether you're engaged in basic research or oncology studies, this antibody is a valuable asset, providing you with the confidence to advance your scientific inquiries and make significant strides in your work.

Product Name

ERCC3 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

BACKGROUND

This gene encodes an ATP-dependent DNA helicase that functions in nucleotide excision repair. The encoded protein is a subunit of basal transcription factor 2 (TFIIH) and, therefore, also functions in class II transcription. Mutations in this gene are associated with Xeroderma pigmentosum B, Cockayne's syndrome, and trichothiodystrophy. Alternative splicing results in multiple transcript variants.

IMMUNOGEN INFORMATION

Immunogen

excision repair cross-complementing rodent repair deficiency, complementation group 3 (xeroderma pigmentosum group B complementing)

Synonyms

XPB, XPBC

Observed MW

80 kDa

APPLICATION

Tested Application

ELISA, IHC, WB

Recommended Dilution

WB: 1:500 - 1:2000; IHC: 1:50 - 1:200

UNIPROT INFORMATION

UniProt ID

P19447

IMAGES