anti- ERCC6 antibody

Delve into the complex world of DNA repair and genomic stability with our Anti-ERCC6 Antibody, an essential tool for studying ERCC6, a key component of the DNA repair machinery. With 100µg of high-quality antibody, you have the precision and reliability required for your experiments.

ERCC6 plays a pivotal role in the repair of DNA damage, preventing mutations, and safeguarding genomic integrity. Our antibody is meticulously tested for specificity and sensitivity, ensuring accurate results in techniques such as immunoblotting, immunoprecipitation, and immunofluorescence.

The Anti-ERCC6 Antibody is your essential tool for exploring ERCC6's functions with precision, contributing to a deeper understanding of DNA repair and genome maintenance. Whether you're engaged in basic research or oncology studies, this antibody is a valuable asset, providing you with the confidence to advance your scientific inquiries and make significant strides in your work.

Product Name

ERCC6 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Essential factor involved in transcription-coupled nucleotide excision repair which allows RNA polymerase II-blocking lesions to be rapidly removed from the transcribed strand of active genes. Upon DNA-binding, it locally modifies DNA conformation by wrapping the DNA around itself, thereby modifying the interface between stalled RNA polymerase II and DNA. It is required for transcription-coupled repair complex formation. It recruits the CSA complex(DCX(ERCC8) complex), nucleotide excision repair proteins and EP300 to the at sites of RNA polymerase II-blocking lesions.

IMMUNOGEN INFORMATION

Immunogen

excision repair cross-complementing rodent repair deficiency, complementation group 6

Synonyms

CSB

Observed MW

150kd

APPLICATION

Tested Application

ELISA, WB

Recommended Dilution

WB: 1:500-1:2000

UNIPROT INFORMATION

UniProt ID

Q03468

IMAGES