anti- ERK1/2 antibody

Unleash the power of signal transduction research with our Anti-ERK1/2 Antibody, an invaluable tool for the study of Extracellular Signal-Regulated Kinases 1 and 2. With 100µg of this high-quality antibody, you possess the precision and reliability required for your experiments.

ERK1 and ERK2 are central components of the MAPK signaling pathway, regulating cell proliferation, differentiation, and response to extracellular cues. Our antibody is rigorously tested for specificity and sensitivity, making it ideal for techniques such as immunoblotting, immunoprecipitation, and immunofluorescence.

The Anti-ERK1/2 Antibody is your passport to understanding the functions of ERK1 and ERK2, their roles in cellular signaling, and their implications in cancer, immunology, and neurobiology research. Whether you're engaged in basic research or drug development, this antibody is an indispensable asset, providing you with the confidence to advance your scientific inquiries and make significant strides in your work.

Product Name

ERK1/2 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

BACKGROUND

The protein encoded by this gene is a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act in a signaling cascade that regulates various cellular processes such as proliferation, differentiation, and cell cycle progression in response to a variety of extracellular signals. This kinase is activated by upstream kinases, resulting in its translocation to the nucleus where it phosphorylates nuclear targets. Alternatively spliced transcript variants encoding different protein isoforms have been described.

IMMUNOGEN INFORMATION

Immunogen

mitogen-activated protein kinase 3

Synonyms

ERK, ERK 1, ERK1, ERK1/2, ERT2, HS44KDAP, HUMKER1A, Insulin stimulated MAP2 kinase, MAP kinase 3, MAP kinase isoform p44, MAPK 3, MAPK3, p44 ERK1, p44 MAPK, P44ERK1, P44MAPK, PRKM3

Observed MW

40 kDa

APPLICATION

Tested Application

ELISA, WB, IHC

Recommended Dilution

WB: 1:500 - 1:2000; IHC: 1:50 - 1:200

UNIPROT INFORMATION

UniProt ID

P27361

IMAGES