1 1

FineTest

FNab02846

anti- ERK1/2 antibody

anti- ERK1/2 antibody

$310.00 USD
$310.00 USD
Sale Sold out
Shipping calculated at checkout.
size

Enhance your research capabilities with our set of two Anti-ERK1/2 Antibodies, designed to empower your investigations into the complex signaling pathways regulated by extracellular signal-regulated kinases 1 and 2 (ERK1/2). Each vial contains 100µg of high-quality antibody, providing you with the precision and reliability needed for your experiments.

ERK1 and ERK2 are key components of the mitogen-activated protein kinase (MAPK) pathway, governing various cellular processes, including cell proliferation, differentiation, and survival. Our antibodies are meticulously tested for specificity and sensitivity, making them ideal for techniques such as immunoblotting, immunoprecipitation, and immunofluorescence.

The Anti-ERK1/2 Antibody set is your essential resource for investigating the multifaceted roles of ERK1/2 in cell signaling and their contributions to a wide range of physiological and pathological conditions. Whether you're engaged in basic research or exploring diseases related to MAPK signaling, this antibody set is an invaluable asset, providing you with the confidence to advance your scientific inquiries and make significant strides in your work.

Product Name

ERK1/2 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

ERK1 and ERK2 belongs to the protein kinase superfamily. It is involved in both the initiation and regulation of meiosis, mitosis, and postmitotic functions in differentiated cells by phosphorylating a number of transcription factors such as ELK-1. ERK1/2 catalized the reaction: ATP + a protein = ADP + a phosphoprotein. It is activated by tyrosine phosphorylation in response to insulin and NGF. This antibody can recognize both ERK1 and ERK2 with the molecular mass of 38-44 kDa.

IMMUNOGEN INFORMATION

Immunogen

mitogen-activated protein kinase 1

Synonyms

ERK, ERK 2, ERK1/2, ERK2, ERT1, MAP kinase 1, MAP kinase 2, MAP kinase isoform p42, MAPK 1, MAPK 2, MAPK1, MAPK2, p40, p41, p41mapk, p42 MAPK, P42MAPK, PRKM1, PRKM2

Observed MW

38-44 kDa

APPLICATION

Tested Application

ELISA, WB, IHC, IF

Recommended Dilution

WB: 1:500-1:3000; IHC: 1:50-1:500; IF: 1:10-1:100

UNIPROT INFORMATION

UniProt ID

P28482

IMAGES

 

Immunohistochemistry of paraffin-embedded human colon cancer tissue slide using FNab02846(ERK1/2 Antibody) at dilution of 1:200 heat mediated antigen retrieved with Tris-EDTA buffer(pH9).
Immunofluorescent analysis of Hela cells, using FNab02846(ERK1/2 Antibody) at 1:25 dilution. Blue pseudocolor = DAPI (fluorescent DNA dye).
HeLa cells were subjected to SDS PAGE followed by western blot with FNab02846(ERK1/2 antibody) at dilution of 1:1000

 

View full details