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SKU:FNab02848

anti- ERLIN1 antibody

anti- ERLIN1 antibody

Regular price $290.00 USD
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Uncover the mysteries of endoplasmic reticulum lipid raft-associated proteins with our Anti-ERLIN1 Antibody, a crucial tool for your scientific inquiries. With 100µg of high-quality antibody, you have the precision and reliability required for your experiments.

ERLIN1, a key component of lipid raft domains in the endoplasmic reticulum, plays a vital role in lipid metabolism and membrane stability. Our antibody is meticulously tested for specificity and sensitivity, making it ideal for techniques such as immunoblotting, immunoprecipitation, and immunofluorescence.

The Anti-ERLIN1 Antibody is your essential tool for exploring the functions of ERLIN1 with precision, contributing to a deeper understanding of lipid homeostasis, membrane dynamics, and its implications in various cellular processes. Whether you're engaged in basic research or lipid-related disease studies, this antibody is an invaluable asset, providing you with the confidence to advance your scientific inquiries and make significant strides in your work.

Product Name

ERLIN1 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Component of the ERLIN1/ERLIN2 complex which mediates the endoplasmic reticulum-associated degradation(ERAD) of inositol 1,4,5-trisphosphate receptors(IP3Rs). Involved in regulation of cellular cholesterol homeostasis by regulation the SREBP signaling pathway. Binds cholesterol and may promote ER retention of the SCAP-SREBF complex(PubMed:24217618).

IMMUNOGEN INFORMATION

Immunogen

ER lipid raft associated 1

Synonyms

C10orf69, KE04, KEO4, SPFH1

Observed MW

39 kDa

APPLICATION

Tested Application

ELISA, WB, IHC, IP, IF

Recommended Dilution

WB: 1:500-1:2000; IP: 1:200-1:2000; IHC: 1:20-1:200; IF: 1:20-1:200

UNIPROT INFORMATION

UniProt ID

O75477

IMAGES

 

Immunohistochemistry of paraffin-embedded human testis using FNab02848(ERLIN1 antibody) at dilution of 1:100
IP Result of anti-ERLIN1 (IP:FNab02848, 3ug; Detection:FNab02848 1:1000) with mouse heart tissue lysate 4000ug.
rat pancreas tissue were subjected to SDS PAGE followed by western blot with FNab02848(ERLIN1 antibody) at dilution of 1:500
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