anti- ERLIN2 antibody

Immerse yourself in the intricate world of endoplasmic reticulum lipid raft-associated proteins with our Anti-ERLIN2 Antibody, an essential tool for your research needs. With 100µg of high-quality antibody, you have the precision and reliability required for your experiments.

ERLIN2, a crucial component of lipid raft domains in the endoplasmic reticulum, is involved in lipid metabolism and membrane homeostasis. Our antibody is rigorously tested for specificity and sensitivity, making it ideal for techniques such as immunoblotting, immunoprecipitation, and immunofluorescence.

The Anti-ERLIN2 Antibody is your indispensable tool for exploring the functions of ERLIN2, contributing to a deeper understanding of lipid metabolism, membrane dynamics, and its implications in cellular processes. Whether you're involved in basic research or lipid-related disease studies, this antibody is an invaluable asset, providing you with the confidence to advance your scientific inquiries and make significant strides in your work.

Product Name

ERLIN2 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Component of the ERLIN1/ERLIN2 complex which mediates the endoplasmic reticulum-associated degradation(ERAD) of inositol 1,4,5-trisphosphate receptors(IP3Rs) such as ITPR1(PubMed:19240031, PubMed:17502376). Promotes sterol-accelerated ERAD of HMGCR probably implicating an AMFR/gp78-containing ubiquitin ligase complex(PubMed:21343306). Involved in regulation of cellular cholesterol homeostasis by regulation the SREBP signaling pathway. May promote ER retention of the SCAP-SREBF complex(PubMed:24217618).

IMMUNOGEN INFORMATION

Immunogen

ER lipid raft associated 2

Synonyms

C8orf2, SPFH2

Observed MW

38 kDa

APPLICATION

Tested Application

ELISA, WB

Recommended Dilution

WB: 1:500-1:2000

UNIPROT INFORMATION

UniProt ID

O94905

IMAGES