anti- ERp57/ERp60 antibody

Immerse yourself in the intricate world of protein disulfide isomerases (PDIs) with our Anti-ERp57/ERp60 Antibody, an essential tool for studying ERp57 and ERp60, two key members of the PDI family. With 100µg of high-quality antibody, you have the precision and reliability required for your experiments.

ERp57 and ERp60 are critical players in catalyzing disulfide bond formation in proteins, ensuring proper protein folding and quality control. Our antibody is meticulously tested for specificity and sensitivity, making it ideal for techniques such as immunoblotting, immunoprecipitation, and immunofluorescence.

The Anti-ERp57/ERp60 Antibody is your indispensable tool for exploring the functions of ERp57 and ERp60 with precision, contributing to a deeper understanding of protein homeostasis and quality control. Whether you're engaged in basic research or investigating protein folding diseases, this antibody is a valuable asset, providing you with the confidence to advance your scientific inquiries and make significant strides in your work.

Product Name

ERp57/ERp60 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

PDIA3, also named as P58, ER60, ERp57, ERp60, ERp61, GRP57, GRP58 and PI-PLC, is a member of the PDI family, participates in the oxidation, reduction, and isomerization of disulfide bonds for correct folding of secretory proteins before modification and transport in the endoplasmic reticulum. It is associated with apoptosis or inhibition of cancer cell growth. PDIA3 was once thought to be a phospholipase; however, it has been demonstrated that this protein actually has protein disulfide isomerase activity. It is thought that complexes of lectins and PDIA3 mediate protein folding by promoting formation of disulfide bonds in their glycoprotein substrates.

IMMUNOGEN INFORMATION

Immunogen

protein disulfide isomerase family A, member 3

Synonyms

58 kDa microsomal protein, Disulfide isomerase ER 60, ER protein 57, ER protein 60, ER60, ERp57, ERp60, ERp61, GRP57, GRP58, HsT17083, P58, PDIA3, PI PLC, Protein disulfide isomerase A3

Observed MW

57 kDa

APPLICATION

Tested Application

ELISA, WB, IHC, IF, FC, IP

Recommended Dilution

WB: 1:500-1:2400; IP: 1:1000-1:4000; IHC: 1:20-1:200; IF: 1:20-1:200

UNIPROT INFORMATION

UniProt ID

P30101

IMAGES