anti- ESR2 antibody

Dive into the intricate world of estrogen receptors and hormonal signaling with our Anti-ESR2 Antibody, a crucial tool for your research needs. With 100µg of high-quality antibody, you have the precision and reliability required for your experiments.

ESR2, also known as estrogen receptor beta, is a key player in regulating responses to estrogen, impacting various physiological processes and influencing cancer development. Our antibody is rigorously tested for specificity and sensitivity, making it ideal for techniques such as immunoblotting, immunoprecipitation, and immunofluorescence.

The Anti-ESR2 Antibody is your gateway to understanding the functions of ESR2 and its contributions to hormonal biology and cancer research. Whether you're engaged in basic research or hormone therapy development, this antibody is an invaluable asset, providing you with the confidence to advance your scientific inquiries and make significant strides in your work.

Product Name

ESR2 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

BACKGROUND

This gene encodes a member of the family of estrogen receptors and superfamily of nuclear receptor transcription factors. The gene product contains an N-terminal DNA binding domain and C-terminal ligand binding domain and is localized to the nucleus, cytoplasm, and mitochondria. Upon binding to 17beta-estradiol or related ligands, the encoded protein forms homo- or hetero-dimers that interact with specific DNA sequences to activate transcription. Some isoforms dominantly inhibit the activity of other estrogen receptor family members. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been fully characterized.

IMMUNOGEN INFORMATION

Immunogen

estrogen receptor 2 (ER beta)

Synonyms

ESTRB, NR3A2

Observed MW

55-60 kDa

APPLICATION

Tested Application

ELISA, IHC, WB

Recommended Dilution

WB: 1:500 - 1:2000; IHC: 1:50 - 1:200

UNIPROT INFORMATION

UniProt ID

Q92731

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