anti- ESRP2 antibody

Unlock the potential of epithelial splicing regulatory protein 2 (ESRP2) with our Anti-ESRP2 Antibody, an essential tool for your scientific investigations. With 100µg of high-quality antibody, you have the precision and reliability required for your experiments.

ESRP2 is a critical regulator of alternative splicing in epithelial cells and plays a pivotal role in the maintenance of epithelial cell characteristics. Dysregulation of splicing events can have profound effects on cell behavior and is associated with various diseases, including cancer. Our antibody is meticulously tested for specificity and sensitivity, making it ideal for techniques such as immunoblotting, immunoprecipitation, and immunohistochemistry.

The Anti-ESRP2 Antibody is your indispensable resource for understanding the functions of ESRP2 and its implications in epithelial biology and disease. Whether you're engaged in basic research or cancer-related studies, this antibody is an invaluable asset, providing you with the confidence to advance your scientific inquiries and make significant strides in your work.

Product Name

ESRP2 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

mRNA splicing factor that regulates the formation of epithelial cell-specific isoforms. Specifically regulates the expression of FGFR2-IIIb, an epithelial cell-specific isoform of FGFR2. Also regulates the splicing of CD44, CTNND1, ENAH, 3 transcripts that undergo changes in splicing during the epithelial-to-mesenchymal transition(EMT). Acts by directly binding specific sequences in mRNAs. Binds the GU-rich sequence motifs in the ISE/ISS-3, a cis-element regulatory region present in the mRNA of FGFR2.

IMMUNOGEN INFORMATION

Immunogen

epithelial splicing regulatory protein 2

Synonyms

RBM35B

Observed MW

78 kDa

APPLICATION

Tested Application

ELISA, WB

Recommended Dilution

WB: 1:500-1:2000

UNIPROT INFORMATION

UniProt ID

Q9H6T0

IMAGES