anti- ESX1 antibody

Unveil the secrets of ESX1 with our Anti-ESX1 Antibody, an essential tool for your scientific investigations. With 100µg of high-quality antibody, you have the precision and reliability required for your experiments.

ESX1, also known as ESAT-6-like protein 1, is a crucial player in mycobacterial physiology and virulence. It is a part of the ESX-1 (Type VII) secretion system, which is integral for the pathogenicity of Mycobacterium tuberculosis, the causative agent of tuberculosis. Our antibody is rigorously tested for specificity and sensitivity, making it ideal for techniques such as immunoblotting, immunoprecipitation, and immunofluorescence.

The Anti-ESX1 Antibody is your indispensable tool for unraveling the functions of ESX1 and its role in the complex interplay between the pathogen and the host. Whether you're engaged in basic research on mycobacterial infections or drug discovery, this antibody is an invaluable asset, providing you with the confidence to advance your scientific inquiries and make significant strides in your work.

Product Name

ESX1 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

May coordinately regulate cell cycle progression and transcription during spermatogenesis. Inhibits degradation of polyubiquitinated cyclin A and cyclin B1 and thereby arrests the cell cycle at early M phase. ESXR1-N acts as a transcriptional repressor. Binds to the sequence 5'-TAATGTTATTA-3' which is present within the first intron of the KRAS gene and inhibits its expression. ESXR1-C has the ability to inhibit cyclin turnover.

IMMUNOGEN INFORMATION

Immunogen

ESX homeobox 1

Synonyms

ESX1L, ESX1R

Observed MW

65 kDa

APPLICATION

Tested Application

ELISA, WB, IP

Recommended Dilution

WB: 1:500-1:2000; IP: 1:200-1:2000

UNIPROT INFORMATION

UniProt ID

Q8N693

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