anti- ETFA antibody

Embark on a journey into the world of electron transfer flavoprotein (ETF) with our Anti-ETFA Antibody, an essential tool for your research endeavors. With 100µg of high-quality antibody, you have the precision and reliability required for your experiments.

ETFA, a component of the ETF complex, is a vital player in the transfer of electrons from fatty acid beta-oxidation and amino acid catabolism to the respiratory chain. Mutations in the ETFA gene are associated with multiple acyl-coenzyme A dehydrogenase deficiency (MADD), a rare metabolic disorder. Our antibody is rigorously tested for specificity and sensitivity, making it ideal for techniques such as immunoblotting, immunohistochemistry, and enzyme assays.

The Anti-ETFA Antibody is your indispensable tool for investigating the functions of ETFA and its implications in metabolic disorders. Whether you're engaged in basic research or studying MADD, this antibody is an invaluable asset, providing you with the confidence to advance your scientific inquiries and make significant strides in your work.

Product Name

ETFA antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

BACKGROUND

ETFA participates in catalyzing the initial step of the mitochondrial fatty acid beta-oxidation. It shuttles electrons between primary flavoprotein dehydrogenases and the membrane-bound electron transfer flavoprotein ubiquinone oxidoreductase. Defects in electron-transfer-flavoprotein have been implicated in type II glutaricaciduria in which multiple acyl-CoA dehydrogenase deficiencies result in large excretion of glutaric, lactic, ethylmalonic, butyric, isobutyric, 2-methyl-butyric, and isovaleric acids. Two transcript variants encoding different isoforms have been found for this gene.

IMMUNOGEN INFORMATION

Immunogen

electron-transfer-flavoprotein, alpha polypeptide

Observed MW

35 kDa

APPLICATION

Tested Application

ELISA, WB, IHC, IF

Recommended Dilution

WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:100

UNIPROT INFORMATION

UniProt ID

P13804

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