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FineTest

SKU:FNab02889

anti- EXD1 antibody

anti- EXD1 antibody

Regular price $290.00 USD
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Embark on a journey of discovery with our Anti-EXD1 Antibody, a crucial tool for your scientific explorations. With 100µg of high-quality antibody, you have the precision and reliability required for your experiments.

EXD1, an exosome complex component, is involved in critical cellular processes such as RNA processing and degradation. It has garnered significant attention in the fields of molecular biology and RNA research. Our antibody is meticulously tested for specificity and sensitivity, making it ideal for techniques like immunoblotting, immunoprecipitation, and immunofluorescence.

The Anti-EXD1 Antibody is your essential resource for understanding the functions of EXD1 and its contributions to exosome-related processes. Whether you are engaged in basic research or exploring RNA biology, this antibody is an invaluable asset, providing you with the confidence to advance your scientific inquiries and make significant strides in your work.

Product Name

EXD1 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

RNA-binding component of the PET complex, a multiprotein complex required for the processing of piRNAs during spermatogenesis. The piRNA metabolic process mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposable elements, preventing their mobilization, which is essential for the germline integrity(By similarity). The PET complex is required during the secondary piRNAs metabolic process for the PIWIL2 slicing-triggered loading of PIWIL4 piRNAs. In the PET complex, EXD1 probably acts as an RNA adapter. EXD1 is an inactive exonuclease(By similarity).

IMMUNOGEN INFORMATION

Immunogen

exonuclease 3'-5' domain containing 1

Synonyms

EXDL1

Observed MW

36 kDa

APPLICATION

Tested Application

ELISA, WB, IHC, IF

Recommended Dilution

WB: 1:200-1:1000; IHC: 1:50-1:500; IF: 1:20-1:200

UNIPROT INFORMATION

UniProt ID

Q8NHP7

IMAGES

 

Immunohistochemistry of paraffin-embedded human testis tissue slide using FNab02889( EXD1 antibody) at dilution of 1:200
HeLa cells were subjected to SDS PAGE followed by western blot with FNab02889( EXD1 Antibody) at dilution of 1:300

 

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