anti- EYA2 antibody

Unveil the mysteries of developmental biology with our Anti-EYA2 Antibody, a vital tool for studying EYA2's role in organogenesis and tissue-specific processes. EYA2 is recognized for its involvement in cellular development and signaling pathways, making it a pivotal target for researchers exploring developmental biology and disease mechanisms. This high-quality antibody, available in a 100µg size, is your trusted partner in unraveling the intricacies of EYA2's functions.

Our meticulously developed and rigorously validated Anti-EYA2 Antibody ensures exceptional specificity and sensitivity, providing you with reliable and accurate results in your research. Whether you're studying organ development, signaling pathways, or other aspects of cellular function, this antibody offers versatility and high performance.

The 100µg size minimizes the need for frequent reordering, allowing you to focus more on your research and less on supply management. Whether you're working with tissue samples, cell cultures, or other experimental systems, this antibody seamlessly adapts to a wide range of research applications.

Product Name

EYA2 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Functions both as protein phosphatase and as transcriptional coactivator for SIX1, and probably also for SIX2, SIX4 and SIX5(PubMed:12500905, PubMed:23435380). Tyrosine phosphatase that dephosphorylates 'Tyr-142' of histone H2AX(H2AXY142ph) and promotes efficient DNA repair via the recruitment of DNA repair complexes containing MDC1. 'Tyr-142' phosphorylation of histone H2AX plays a central role in DNA repair and acts as a mark that distinguishes between apoptotic and repair responses to genotoxic stress(PubMed:19351884). Its function as histone phosphatase may contribute to its function in transcription regulation during organogenesis. Plays an important role in hypaxial muscle development together with SIX1 and DACH2; in this it is functionally redundant with EYA1(PubMed:12500905).

IMMUNOGEN INFORMATION

Immunogen

eyes absent homolog 2(Drosophila)

Synonyms

EAB1

Observed MW

57 kDa

APPLICATION

Tested Application

ELISA, WB, IHC

Recommended Dilution

WB: 1:500-1:2000; IHC: 1:20-1:200

UNIPROT INFORMATION

UniProt ID

O00167

IMAGES