anti- EZH1 antibody

Embark on a journey into the world of epigenetics with our Anti-EZH1 Antibody. Enhancer of Zeste Homolog 1 (EZH1) plays a vital role in histone methylation and gene regulation, contributing to the intricate control of gene expression. This high-quality antibody, available in a 100µg size, is your trusted companion for unlocking the secrets of epigenetic modifications.

Our meticulously developed and rigorously validated Anti-EZH1 Antibody ensures exceptional specificity and sensitivity, providing you with reliable and accurate results in your research. Whether you're exploring gene regulation, epigenetic modifications, or chromatin dynamics, this antibody adapts effortlessly to a wide range of research applications.

With 100µg at your disposal, this antibody minimizes the need for frequent reordering, ensuring a seamless research experience. Whether you're working with cell cultures, tissue samples, or other experimental systems, this antibody offers flexibility and robust performance.

Product Name

EZH1 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Polycomb group(PcG) protein. Catalytic subunit of the PRC2/EED-EZH1 complex, which methylates 'Lys-27' of histone H3, leading to transcriptional repression of the affected target gene. Able to mono-, di-and trimethylate 'Lys-27' of histone H3 to form H3K27me1, H3K27me2 and H3K27me3, respectively. Required for embryonic stem cell derivation and self-renewal, suggesting that it is involved in safeguarding embryonic stem cell identity. Compared to EZH2-containing complexes, it is less abundant in embryonic stem cells, has weak methyltransferase activity and plays a less critical role in forming H3K27me3, which is required for embryonic stem cell identity and proper differentiation.

IMMUNOGEN INFORMATION

Immunogen

enhancer of zeste homolog 1(Drosophila)

Synonyms

KIAA0388

Observed MW

77-86 kDa, 69 kDa

APPLICATION

Tested Application

ELISA, WB

Recommended Dilution

WB: 1:500-1:2000

UNIPROT INFORMATION

UniProt ID

Q92800

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