anti- FANCI antibody

Unlock the secrets of DNA repair and genomic stability with our Anti-FANCI Antibody, a critical tool for investigating the functions of Fanconi anemia complementation group I (FANCI). FANCI is a key player in the Fanconi anemia pathway, a vital mechanism for maintaining genomic integrity. This high-quality antibody, available in a 100µg size, is your trusted partner for delving into the intricacies of FANCI's roles.

Our Anti-FANCI Antibody has been meticulously developed and rigorously validated to ensure exceptional specificity and sensitivity. It empowers you to explore FANCI's multifaceted functions, from its involvement in DNA repair to its implications in cancer, genetic disorders, and beyond, with confidence in the reliability of your results.

With 100µg at your disposal, this antibody minimizes the need for frequent reordering, ensuring a seamless and uninterrupted research experience. Whether you're unraveling the molecular details of DNA repair, dissecting the impact of FANCI mutations, or exploring its potential in cancer therapy, this antibody seamlessly adapts to a wide range of research applications.

Product Name

FANCI antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Plays an essential role in the repair of DNA double-strand breaks by homologous recombination and in the repair of interstrand DNA cross-links(ICLs) by promoting FANCD2 monoubiquitination by FANCL and participating in recruitment to DNA repair sites. Required for maintenance of chromosomal stability. Specifically binds branched DNA: binds both single-stranded DNA(ssDNA) and double-stranded DNA(dsDNA). Participates in S phase and G2 phase checkpoint activation upon DNA damage.

IMMUNOGEN INFORMATION

Immunogen

Fanconi anemia, complementation group I

Synonyms

KIAA1794

Observed MW

150 kDa

APPLICATION

Tested Application

ELISA, WB, IF, IP

Recommended Dilution

WB: 1:500-1:2000; IP: 1:200-1:1000; IF: 1:20-1:200

UNIPROT INFORMATION

UniProt ID

Q9NVI1

IMAGES