anti- FANCL antibody

Explore the intricate world of FANCL (Fanconi anemia complementation group L) with our Anti-FANCL Antibody, a valuable tool for researchers in DNA repair, genome stability, and the Fanconi anemia pathway. FANCL plays a crucial role in the monoubiquitination of FANCD2 and FANCI, contributing to the DNA damage response and genome maintenance. Our high-quality antibody, available in a set of two 100µg vials, delivers the precision and sensitivity needed to explore the functions and regulatory mechanisms of FANCL.

This Anti-FANCL Antibody has undergone meticulous development and rigorous validation to ensure its specificity and reliability. It empowers you to investigate FANCL's role in the Fanconi anemia pathway, its interactions with other Fanconi anemia proteins, and its potential applications in cancer research and understanding genetic diseases.

With two vials of 100µg of this antibody at your disposal, you can minimize the need for frequent reordering, ensuring a smooth and uninterrupted research experience. Whether you are studying FANCL's function in DNA damage repair, its implications in tumor suppression, or its contributions to maintaining genomic integrity, this antibody adapts seamlessly to a wide range of research applications.

Product Name

FANCL antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

BACKGROUND

The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity; they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group L. Alternative splicing results in two transcript variants encoding different isoforms.

IMMUNOGEN INFORMATION

Immunogen

Fanconi anemia, complementation group L

Synonyms

PHF9

Observed MW

38 kDa

APPLICATION

Tested Application

ELISA, WB, IHC

Recommended Dilution

WB: 1:200 - 1:2000; IHC: 1:20 - 1:200

UNIPROT INFORMATION

UniProt ID

Q9NW38

IMAGES