anti- FANCM antibody

Delve into the intricate realm of FANCM with our Anti-FANCM Antibody, a valuable tool for researchers focused on DNA repair, genome stability, and cancer biology. FANCM is a pivotal component of the Fanconi anemia pathway, known for its role in maintaining genomic integrity and protecting against DNA damage. Our high-quality antibody, available in a 100µg size, delivers the precision and sensitivity needed to explore the functions and regulatory mechanisms of FANCM.

This Anti-FANCM Antibody has undergone meticulous development and rigorous validation to ensure its specificity and reliability. It empowers you to investigate FANCM's role in DNA repair, its interactions with other Fanconi anemia proteins, and its potential applications in cancer research and understanding genetic diseases.

With 100µg of this antibody at your disposal, you can minimize the need for frequent reordering, ensuring a smooth and uninterrupted research experience. Whether you are examining FANCM's function in DNA damage response, its implications in tumor suppression, or its contributions to the Fanconi anemia pathway, this antibody adapts seamlessly to a wide range of research applications.

Product Name

FANCM antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

ATPase required for FANCD2 ubiquitination, a key reaction in DNA repair. Binds to ssDNA but not to dsDNA. Recruited to forks stalled by DNA interstrand cross-links, and required for cellular resistance to such lesions.

IMMUNOGEN INFORMATION

Immunogen

Fanconi anemia, complementation group M

Synonyms

KIAA1596

Observed MW

250 kDa, 232 kDa

APPLICATION

Tested Application

ELISA, WB

Recommended Dilution

WB: 1:500-1:2000

UNIPROT INFORMATION

UniProt ID

Q8IYD8

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