anti- FAS/CD95 antibody

Explore the intricate world of FAS/CD95 with our Anti-FAS/CD95 Antibody, an invaluable tool for researchers in immunology, apoptosis, and cancer biology. FAS/CD95 is a cell surface receptor known for its pivotal role in apoptosis, making it a significant target for studies related to immune response and cancer therapy. Our high-quality antibody, available in a 100µg size, provides the precision and sensitivity needed to explore the functions and regulatory mechanisms of FAS/CD95.

This Anti-FAS/CD95 Antibody has undergone meticulous development and rigorous validation to ensure its specificity and reliability. It empowers you to investigate FAS/CD95's role in programmed cell death, its interactions with ligands, and its potential applications in immunotherapy and cancer research.

With 100µg of this antibody at your disposal, you can minimize the need for frequent reordering, ensuring a smooth and uninterrupted research experience. Whether you are studying FAS/CD95's function in autoimmune diseases, its implications in cancer progression, or its contributions to drug development, this antibody adapts effortlessly to a wide range of research applications.

Product Name

FAS/CD95 antibody

Size

100µg

Form

liquid

Purification

Protein A+G purification

Purity

≥95% as determined by SDS-PAGE

Host

Mouse

Clonality

monoclonal

Isotype

IgG2a

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Fas(CD95/APO-1) is a transmembrane glycoprotein belonging to the tumor necrosis factor(TNF) receptor superfamily. It can mediates apoptosis by ligation with an agonistic anti-Fas antibody or Fas ligand. Stimulation of Fas results in the aggregation of its intracellular death domains, leading to the formation of the death-inducing signaling complex(DISC). FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. The molecular mass of native Fas is 38 kDa, the high molecular weight form(40-55 kDa) of Fas is due to glycosylation.

IMMUNOGEN INFORMATION

Immunogen

Fas(TNF receptor superfamily, member 6)

Synonyms

ALPS1A, APO 1, Apo 1 antigen, APT1, CD95, FAS, FAS1, FASLG receptor, FASTM, TNFRSF6

Observed MW

38-45 kDa

APPLICATION

Tested Application

ELISA, WB, FC,IHC

Recommended Dilution

WB: 1:1000-1:8000; IHC: 1:50-1:500

UNIPROT INFORMATION

UniProt ID

P25445

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