anti- FBL antibody

Uncover the intricate functions of Fibrillarin (FBL) with our Anti-FBL Antibody, a valuable tool designed for researchers in the fields of cell biology and molecular biology. FBL is a key player in ribosome biogenesis and other RNA-related processes, making it an important target for studies on gene expression and regulation. Our high-quality antibody, available in a 100µg size, delivers the precision and sensitivity necessary to explore the functions and regulatory mechanisms of FBL.

This Anti-FBL Antibody has been meticulously developed and rigorously validated to ensure its specificity and reliability. It empowers you to study FBL's role in ribosome synthesis, its interactions with various RNA species, and its implications in diseases related to nucleolar stress.

With 100µg of this antibody at your disposal, you can minimize the need for frequent reordering, ensuring a smooth and uninterrupted research experience. Whether you are investigating FBL's role in cancer, its implications in neurodegenerative diseases, or its involvement in RNA modification, this antibody adapts seamlessly to a wide range of research applications.

Product Name

FBL antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

BACKGROUND

This gene product is a component of a nucleolar small nuclear ribonucleoprotein (snRNP) particle thought to participate in the first step in processing preribosomal RNA. It is associated with the U3, U8, and U13 small nuclear RNAs and is located in the dense fibrillar component (DFC) of the nucleolus. The encoded protein contains an N-terminal repetitive domain that is rich in glycine and arginine residues, like fibrillarins in other species. Its central region resembles an RNA-binding domain and contains an RNP consensus sequence. Antisera from approximately 8% of humans with the autoimmune disease scleroderma recognize fibrillarin.

IMMUNOGEN INFORMATION

Immunogen

fibrillarin

Synonyms

FIB1, FLRN

Observed MW

37 kDa

APPLICATION

Tested Application

ELISA, IF, IHC, WB, IP

Recommended Dilution

WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:200; IP： 1:20 - 1:50

UNIPROT INFORMATION

UniProt ID

P22087

IMAGES