FineTest
SKU:FNab03043
anti- FBXO3 antibody
anti- FBXO3 antibody
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mbark on a journey of scientific discovery in the realm of cellular regulation with the Anti-FBXO3 Antibody, available in a substantial 100µg size. FBXO3 is a crucial component of the ubiquitin-proteasome system, orchestrating the degradation of specific proteins and influencing various aspects of cellular function. This meticulously validated antibody is your indispensable tool for understanding the intricacies of cellular dynamics.
Key Features:
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Substantial 100µg Quantity: With 100µg of our Anti-FBXO3 Antibody, you have a considerable amount of material to perform a wide array of experiments, ensuring your research remains both cost-effective and reliable.
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Validation for Reliability: Our Anti-FBXO3 Antibody has undergone comprehensive validation to guarantee specificity and reliability, minimizing the risk of non-specific interactions and ensuring your results are precise.
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Probe Cellular Mechanisms: Investigate the role of FBXO3 in the regulation of protein degradation, cellular mechanisms, and its broader implications in cell biology. Your research may uncover new insights into disease development and therapeutic targets.
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Potential Therapeutic Pathways: Examine potential connections between FBXO3 and various diseases, offering fresh perspectives for therapeutic development and a deeper understanding of disease mechanisms.
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Contribute to Scientific Advancements: Join a community of leading researchers who rely on our Anti-FBXO3 Antibody to advance their understanding of regulatory proteins and their role in maintaining healthy cellular function.
Whether you're unraveling FBXO3's role in protein degradation or investigating its broader connections to diseases, our antibody empowers you to conduct accurate and reliable research, unlocking the mysteries of cellular regulation.
Product Name
FBXO3 antibody
Size
100µg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Host
Rabbit
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
BACKGROUND
Substrate recognition component of the SCF(SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. Mediates the ubiquitination of HIPK2 and probably that of EP300, leading to rapid degradation by the proteasome. In the presence of PML, HIPK2 ubiquitination still occurs, but degradation is prevented. PML, HIPK2 and FBXO3 may act synergically to activate p53/TP53-dependent transactivation.
IMMUNOGEN INFORMATION
Immunogen
F-box protein 3
Synonyms
FBX3
Observed MW
48-50kd
APPLICATION
Tested Application
ELISA, WB
Recommended Dilution
WB: 1:500-1:2000
UNIPROT INFORMATION
UniProt ID
IMAGES

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