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FineTest

SKU:FNab03049

anti- FBXO7 antibody

anti- FBXO7 antibody

Regular price $330.00 USD
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Embark on a journey to uncover the mysteries of cellular regulation with our Anti-FBXO7 Antibody, available in a substantial 100µg size. FBXO7 is a pivotal component of the ubiquitin-proteasome system, intricately involved in governing the degradation of specific proteins and influencing a multitude of cellular functions. This meticulously validated antibody is your key to unlocking the intricate world of cellular dynamics.

Key Features:

  1. Ample 100µg Quantity: The generous 100µg quantity ensures you have enough for a wide range of experiments, making your research cost-effective without compromising on reliability.

  2. Rigorous Validation: Our Anti-FBXO7 Antibody has undergone rigorous validation to ensure specificity and reliability, reducing the risk of non-specific interactions and delivering accurate results.

  3. Unravel Cellular Dynamics: Explore the role of FBXO7 in regulating protein degradation, cellular dynamics, and its broader implications in cell biology. It may provide new insights into disease development and therapeutic targets.

  4. Potential Therapeutic Insights: Investigate the links between FBXO7 and various diseases, offering fresh perspectives for therapeutic development and a deeper understanding of disease mechanisms.

  5. Contribute to Scientific Progress: Join a community of leading researchers who rely on our Anti-FBXO7 Antibody to advance their understanding of regulatory proteins and their significance in maintaining healthy cell function.

Whether you're deciphering FBXO7's role in protein degradation or investigating its broader connections in cellular dynamics, our antibody guarantees precision and reliability in your research.

Product Name

FBXO7 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Substrate recognition component of a SCF(SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Recognizes BIRC2 and DLGAP5. Plays a role downstream of PINK1 in the clearance of damaged mitochondria via selective autophagy(mitophagy) by targeting PARK2 to dysfunctional depolarized mitochondria. Promotes MFN1 ubiquitination.

IMMUNOGEN INFORMATION

Immunogen

F-box protein 7

Synonyms

FBX7

Observed MW

58.5 kDa

APPLICATION

Tested Application

ELISA, WB, IHC, IP

Recommended Dilution

WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200

UNIPROT INFORMATION

UniProt ID

Q9Y3I1

IMAGES

 

Immunohistochemistry of paraffin-embedded human prostate cancer using FNab03049(FBXO7 antibody) at dilution of 1:100
IP Result of anti-FBXO7 (IP:FNab03049, 3ug; Detection:FNab03049 1:800) with mouse testis tissue lysate 4000ug.
HeLa cells were subjected to SDS PAGE followed by western blot with FNab03049(FBXO7 antibody) at dilution of 1:1000

 

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