anti- FDPS antibody

Our Anti-FDPS Antibody, available in a 100µg size, offers you a gateway to unravel the intricacies of the mevalonate pathway, a fundamental metabolic route. This meticulously validated and highly specific antibody empowers you to investigate the function and regulation of Farnesyl Pyrophosphate Synthase (FDPS) and its role in various biological processes.

Key Features:

1. Exploring Metabolic Pathways: FDPS is a key player in the mevalonate pathway, a critical metabolic route involved in the synthesis of isoprenoids, sterols, and other essential compounds. This antibody serves as your guide to understanding the pathway's intricacies.

2. Plentiful Antibody Supply: With 100µg of antibody, you have an abundant resource for numerous experiments, minimizing the need for frequent reordering and ensuring research continuity.

3. Stringently Validated for Specificity: The antibody undergoes rigorous specificity testing to ensure accurate recognition of the target, resulting in dependable and consistent experimental results.

4. Versatile Applications: Investigate FDPS's role in isoprenoid biosynthesis, sterol production, and its potential relevance in diseases linked to the mevalonate pathway. Explore its therapeutic potential.

5. Advancing Metabolic Research: By studying FDPS, you can contribute to a deeper understanding of the mevalonate pathway's molecular mechanisms and its implications for health, disease, and therapeutic development.

6. Facilitating Biochemical Inquiries: Whether you're exploring the regulation of metabolic pathways, isoprenoid synthesis, or the role of FDPS in disease states, this antibody is a versatile asset for your research.

7. Trusted Globally: Researchers worldwide rely on our Anti-FDPS Antibody, highlighting its position as a respected resource in the scientific community.

Product Name

FDPS antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

BACKGROUND

This gene encodes an enzyme that catalyzes the production of geranyl pyrophosphate and farnesyl pyrophosphate from isopentenyl pyrophosphate and dimethylallyl pyrophosphate. The resulting product, farnesyl pyrophosphate, is a key intermediate in cholesterol and sterol biosynthesis, a substrate for protein farnesylation and geranylgeranylation, and a ligand or agonist for certain hormone receptors and growth receptors. Drugs that inhibit this enzyme prevent the post-translational modifications of small GTPases and have been used to treat diseases related to bone resorption. Multiple pseudogenes have been found on chromosomes 1, 7, 14, 15, 21 and X. Multiple transcript variants encoding different isoforms have been found for this gene.

IMMUNOGEN INFORMATION

Immunogen

farnesyl diphosphate synthase (farnesyl pyrophosphate synthetase, dimethylallyltranstransferase, geranyltranstransferase)

Synonyms

FPS, KIAA1293

Observed MW

38 kDa

APPLICATION

Tested Application

ELISA, WB, IHC, IF

Recommended Dilution

WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:100

UNIPROT INFORMATION

UniProt ID

P14324

IMAGES