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FineTest

SKU:FNab03070

anti- FECH antibody

anti- FECH antibody

Regular price $290.00 USD
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Our Anti-FECH Antibody, available in a 100µg size, is your guiding light into the intricate pathway of heme synthesis. This highly specific and well-validated antibody is your key to unraveling the mysteries of FECH (Ferrochelatase), an enzyme essential for the final step in heme biosynthesis.

Key Features:

  1. Illuminating Heme Production: FECH plays a pivotal role in the biosynthesis of heme, an essential molecule for hemoglobin and various enzymes. With this antibody, you can dive deep into understanding the regulation of this critical pathway.

  2. Ample Antibody Supply: The 100µg size ensures you have enough antibody for multiple experiments, avoiding the need for frequent restocking and minimizing interruptions in your research.

  3. Precision and Specificity: The antibody is rigorously validated for specificity, assuring you of reliable and reproducible results. Your research will be built on a foundation of accuracy.

  4. Versatility in Applications: Explore the functions of FECH in heme production, its significance in porphyrias, and its potential role in various diseases. Investigate its therapeutic potential.

  5. Revealing Disease Insights: By studying FECH, you can gain insights into porphyria and other diseases associated with heme metabolism, potentially paving the way for novel treatment strategies.

  6. Empowering Biochemistry: Whether you're examining the regulation of heme biosynthesis, the enzymatic activity of FECH, or the consequences of its dysregulation, this antibody is an indispensable tool for your research.

  7. Trusted by the Scientific Community: Researchers worldwide have successfully employed our Anti-FECH Antibody, solidifying its reputation as a valuable resource in the scientific community.

Product Name

FECH antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

BACKGROUND

The protein encoded by this gene is localized to the mitochondrion, where it catalyzes the insertion of the ferrous form of iron into protoporphyrin IX in the heme synthesis pathway. Mutations in this gene are associated with erythropoietic protoporphyria. Two transcript variants encoding different isoforms have been found for this gene. A pseudogene of this gene is found on chromosome 3.

IMMUNOGEN INFORMATION

Immunogen

ferrochelatase (protoporphyria)

Observed MW

50 kDa

APPLICATION

Tested Application

ELISA, WB, IHC

Recommended Dilution

WB: 1:500 - 1:2000; IHC: 1:50 - 1:100

UNIPROT INFORMATION

UniProt ID

P22830

IMAGES

 

Immunohistochemistry of paraffin-embedded rat heart using FNab03070(FECH antibody) at dilution of 1:100
mouse brain tissue were subjected to SDS PAGE followed by western blot with FNab03070(FECH antibody) at dilution of 1:1000
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