anti- FGB antibody

Investigate the intricacies of fibrinogen with our Anti-FGB Antibody, a meticulously crafted product available in a 100µg vial. Fibrinogen, a key protein in blood clotting, is composed of multiple chains, and the fibrinogen beta chain (FGB) is integral to its function. This highly specific antibody empowers you to delve deep into the world of fibrinogen and enhance your research endeavors with unparalleled precision and reliability.

Key Features:

• Unparalleled Specificity: Our Anti-FGB Antibody is rigorously validated to target FGB with high precision, minimizing the risk of cross-reactivity.
• Versatile Applications: Ideal for a wide range of experimental techniques, including Western blotting, immunoprecipitation, and immunohistochemistry.
• Ample Quantity: The 100µg quantity offers an ample supply for numerous experiments.
• Top-Tier Quality: Manufactured to the highest industry standards, ensuring consistency and reproducibility.
• Advance Your Research: Whether you're investigating blood clotting disorders, cardiovascular health, or coagulation pathways, our Anti-FGB Antibody is your key to unlocking new knowledge.

Shed light on the intricate world of fibrinogen and elevate your research with our Anti-FGB Antibody.

Product Name

FGB antibody

Size

100µg

Form

liquid

Purification

Protein A+G purification

Purity

≥95% as determined by SDS-PAGE

Host

Mouse

Clonality

monoclonal

Isotype

IgG2a

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Cleaved by the protease thrombin to yield monomers which, together with fibrinogen alpha(FGA) and fibrinogen gamma(FGG), polymerize to form an insoluble fibrin matrix. Fibrin has a major function in hemostasis as one of the primary components of blood clots. In addition, functions during the early stages of wound repair to stabilize the lesion and guide cell migration during re-epithelialization. Was originally thought to be essential for platelet aggregation, based on in vitro studies using anticoagulated blood. However subsequent studies have shown that it is not absolutely required for thrombus formation in vivo. Enhances expression of SELP in activated platelets. Maternal fibrinogen is essential for successful pregnancy. Fibrin deposition is also associated with infection, where it protects against IFNG-mediated hemorrhage. May also facilitate the antibacterial immune response via both innate and T-cell mediated pathways.

IMMUNOGEN INFORMATION

Immunogen

fibrinogen beta chain

Synonyms

FGB, fibrinogen beta chain

Observed MW

50 kDa

APPLICATION

Tested Application

ELISA, WB

Recommended Dilution

WB: 1:500 - 1:2000

UNIPROT INFORMATION

UniProt ID

P02675

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