anti- FMR1 antibody

Delve into the complexities of Fragile X Syndrome research with our Anti-FMR1 Antibody, available in a 100µg vial. FMR1, the gene associated with Fragile X Syndrome, is vital for understanding neurodevelopment and synaptic function. This highly specific antibody empowers researchers to investigate FMR1 expression and its implications in neurobiology and developmental disorders.

Key Features:

• Exceptional Specificity: Our Anti-FMR1 Antibody is rigorously tested to ensure it accurately targets FMR1, minimizing the risk of cross-reactivity.
• Versatile Applications: Ideal for various experimental techniques, including immunohistochemistry, Western blotting, and RNA immunoprecipitation.
• Ample Quantity: With 100µg, you have a generous supply for multiple experiments.
• Top-Tier Quality: Manufactured to the highest industry standards, guaranteeing consistent and reproducible results.
• Advance Your Research: Whether you're exploring neurodevelopment, synaptic function, or the molecular underpinnings of Fragile X Syndrome, our Anti-FMR1 Antibody is your key to unraveling the mysteries of this condition.

Product Name

FMR1 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

BACKGROUND

The protein encoded by this gene binds RNA and is associated with polysomes. The encoded protein may be involved in mRNA trafficking from the nucleus to the cytoplasm. A trinucleotide repeat (CGG) in the 5' UTR is normally found at 6-53 copies, but an expansion to 55-230 repeats is the cause of fragile X syndrome. Expansion of the trinucleotide repeat may also cause one form of premature ovarian failure (POF1). Multiple alternatively spliced transcript variants that encode different protein isoforms and which are located in different cellular locations have been described for this gene.

IMMUNOGEN INFORMATION

Immunogen

fragile X mental retardation 1

Synonyms

FMRP

Observed MW

85 kDa

APPLICATION

Tested Application

ELISA, WB, IHC, IF

Recommended Dilution

WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:200

UNIPROT INFORMATION

UniProt ID

Q06787

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