anti- G3BP1 antibody

Delve into the world of cellular stress responses and RNA processing with our Anti-G3BP1 Antibody, available in a 100µg size. G3BP1 (Ras GTPase-activating protein-binding protein 1) is a crucial component in stress granule formation, playing a pivotal role in the cell's response to stress. This antibody is tailored to specifically target G3BP1, enabling you to explore its functions with precision.

Key Features:

• Exceptional Specificity: Thoroughly validated to exclusively bind to G3BP1, minimizing the potential for cross-reactivity with other proteins.
• Versatile Applications: Ideal for various experimental techniques, including Western blotting, immunofluorescence, and immunoprecipitation, empowering your research in cellular stress responses and RNA metabolism.
• Sufficient Quantity: With 100µg of antibody, you have enough material for multiple experiments, reducing the need for frequent restocking.
• Quality Guaranteed: Manufactured under stringent quality control measures to ensure the consistency and reliability of your results.
• Uncover Stress Granule Dynamics: Whether you're probing G3BP1's involvement in mRNA processing, neurodegenerative diseases, or cellular response to environmental stress, our Anti-G3BP1 Antibody is your indispensable tool.

Product Name

G3BP1 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

May be a regulated effector of stress granule assembly. Phosphorylation-dependent sequence-specific endoribonuclease in vitro. Cleaves exclusively between cytosine and adenine and cleaves MYC mRNA preferentially at the 3'-UTR. ATP-and magnesium-dependent helicase. Unwinds preferentially partial DNA and RNA duplexes having a 17 bp annealed portion and either a hanging 3' tail or hanging tails at both 5'-and 3'-ends. Unwinds DNA/DNA, RNA/DNA, and RNA/RNA substrates with comparable efficiency. Acts unidirectionally by moving in the 5' to 3' direction along the bound single-stranded DNA.

IMMUNOGEN INFORMATION

Immunogen

GTPase activating protein(SH3 domain) binding protein 1

Synonyms

G3BP

Observed MW

55-60 kDa

APPLICATION

Tested Application

ELISA, WB, IP, IF, IHC, FC

Recommended Dilution

WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200; IF: 1:20-1:200

UNIPROT INFORMATION

UniProt ID

Q13283

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