anti- GAA antibody

Embark on a journey into the world of cellular homeostasis with our Anti-GAA Antibody, offered in a 100µg size. GAA (Glucosidase Alpha) is a critical enzyme involved in the breakdown of glycogen in lysosomes. This antibody is designed to specifically target GAA, enabling you to study its functions in glycogen metabolism and lysosomal storage disorders.

Key Features:

• Precise Targeting: Thoroughly validated to exclusively recognize GAA, minimizing the potential for cross-reactivity with other proteins.
• Versatile Applications: Ideal for various experimental techniques, including Western blotting, immunofluorescence, and immunoprecipitation, facilitating comprehensive research on glycogen metabolism and lysosomal disorders.
• Ample Quantity: With 100µg of antibody, you'll have enough material for multiple experiments, reducing the need for frequent restocking.
• Quality Guaranteed: Manufactured under stringent quality control measures to ensure the consistency and reliability of your results.
• Uncover GAA's Roles: Whether you're delving into glycogen storage diseases, lysosomal enzyme deficiency, or investigating potential therapies, our Anti-GAA Antibody is your indispensable tool.

Product Name

GAA antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

GAA(Alpha-1,4-glucosidase) is a lysosomal enzyme involved in the degradation of glycogen within cellular vacuoles. After translation, GAA undergoes proteolytic processing to form two lengths of lysosomal a-glucosidase, and both N-terminal and C-terminal processing occur. The full sequence can be further processed into a mature form. The 105 kDa GAA can be cleaved into 70 kDa or 76 kDa form.

IMMUNOGEN INFORMATION

Immunogen

Lysosomal alpha-glucosidase

Synonyms

Acid maltase, Aglucosidase alfa, GAA, glucosidase, alpha; acid, LYAG, Lysosomal alpha glucosidase

Observed MW

70-76 kDa

APPLICATION

Tested Application

ELISA, WB, IHC, IP

Recommended Dilution

WB: 1:500-1:1000; IP: 1:500-1:1000; IHC: 1:20-1:200

UNIPROT INFORMATION

UniProt ID

P10253

IMAGES