anti- GABRA1 antibody

Delve into the intricacies of brain function and inhibitory neurotransmission with our Anti-GABRA1 Antibody, available in a 100µg size. GABRA1 (Gamma-Aminobutyric Acid Type A Receptor Subunit Alpha-1) is an essential subunit of GABA(A) receptors, playing a pivotal role in mediating the effects of the inhibitory neurotransmitter GABA. This antibody is expertly crafted to specifically target GABRA1, allowing you to study its functions with precision.

Key Features:

• Precise Targeting: Rigorously validated to exclusively recognize GABRA1, reducing the risk of non-specific binding to other proteins.
• Versatile Applications: Suitable for various experimental techniques, including Western blotting, immunofluorescence, and immunoprecipitation, empowering your research in neurobiology and synaptic transmission.
• Adequate Quantity: With 100µg of antibody, you have enough material for multiple experiments, reducing the need for frequent restocking.
• Quality Guaranteed: Manufactured under stringent quality control measures to ensure the consistency and reliability of your results.
• Unveil Neurological Mechanisms: Whether you're investigating GABRA1's role in epilepsy, sleep disorders, or the GABAergic system, our Anti-GABRA1 Antibody is your indispensable tool.

• Product Name

  GABRA1 antibody

  Size

  100µg

  Form

  liquid

  Purification

  Immunogen affinity purified

  Purity

  ≥95% as determined by SDS-PAGE

  Host

  Rabbit

  Clonality

  polyclonal

  Isotype

  IgG

  Storage

  PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

  BACKGROUND

  Component of the heteropentameric receptor for GABA, the major inhibitory neurotransmitter in the vertebrate brain. Functions also as histamine receptor and mediates cellular responses to histamine. Functions as receptor for diazepines and various anesthetics, such as pentobarbital; these are bound at a separate allosteric effector binding site. Functions as ligand-gated chloride channel(By similarity).

  IMMUNOGEN INFORMATION

  Immunogen

  gamma-aminobutyric acid(GABA) A receptor, alpha 1

  Observed MW

  52 kDa

  APPLICATION

  Tested Application

  ELISA, WB, IP

  Recommended Dilution

  WB: 1:500-1:2000; IP: 1:200-1:2000

  UNIPROT INFORMATION

  UniProt ID

  P14867

  IMAGES

   

  

  IP Result of anti-GABRA1 (IP:FNab03283, 3ug; Detection:FNab03283 1:400) with mouse brain tissue lysate 3600ug.

  

  mouse brain tissue were subjected to SDS PAGE followed by western blot with FNab03283(GABRA1 antibody) at dilution of 1:1000