anti- GADD45A antibody

Delve into the intricacies of cellular stress responses with our Anti-GADD45A Antibody, available in a 100µg size. GADD45A (Growth Arrest and DNA Damage-Inducible Protein A) is a critical component of stress signaling pathways, with pivotal roles in DNA repair and cell cycle regulation. This antibody is meticulously designed to specifically target GADD45A, enabling you to explore its functions with precision.

Key Features:

• Exceptional Specificity: Thoroughly validated to exclusively bind to GADD45A, minimizing the potential for cross-reactivity with other proteins.
• Versatile Applications: Ideal for various experimental techniques, including Western blotting, immunofluorescence, and immunoprecipitation, empowering your research in stress responses and DNA repair.
• Sufficient Quantity: With 100µg of antibody, you have enough material for multiple experiments, reducing the need for frequent restocking.
• Quality Guaranteed: Manufactured under stringent quality control measures to ensure the consistency and reliability of your results.
• Uncover Stress Response Mechanisms: Whether you're probing GADD45A's involvement in genomic stability, cancer therapy, or cell cycle control, our Anti-GADD45A Antibody is your indispensable tool.

• Product Name

  GADD45A antibody

  Size

  100µg

  Form

  liquid

  Purification

  Immunogen affinity purified

  Purity

  ≥95% as determined by SDS-PAGE

  Host

  Rabbit

  Clonality

  polyclonal

  Isotype

  IgG

  Storage

  PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

  BACKGROUND

  In T-cells, functions as a regulator of p38 MAPKs by inhibiting p88 phosphorylation and activity(By similarity). Might affect PCNA interaction with some CDK(cell division protein kinase) complexes; stimulates DNA excision repair in vitro and inhibits entry of cells into S phase.

  IMMUNOGEN INFORMATION

  Immunogen

  growth arrest and DNA-damage-inducible, alpha

  Synonyms

  DDIT1, GADD45

  Observed MW

  18 kDa or 25 kDa

  APPLICATION

  Tested Application

  ELISA, WB

  Recommended Dilution

  WB: 1:500 - 1:2000

  UNIPROT INFORMATION

  UniProt ID

  P24522

  IMAGES

   

  

  MCF7 cells were subjected to SDS PAGE followed by western blot with FNab03294(GADD45A antibody) at dilution of 1:1000