anti- GADD45GIP1 antibody

Investigate GADD45GIP1 (Growth arrest and DNA-damage-inducible protein GADD45 gamma-interacting protein 1) with our Anti-GADD45GIP1 Antibody, available in a 100µg size. GADD45GIP1 is known for its involvement in cellular responses to DNA damage and its potential implications in cancer and DNA repair mechanisms. This antibody is meticulously designed to specifically target GADD45GIP1, enabling you to explore its functions with precision.

Key Features:

• Precise Targeting: Rigorously validated for exclusive recognition of GADD45GIP1, reducing the risk of cross-reactivity with other proteins.
• Versatile Applications: Suitable for various experimental techniques, including immunoprecipitation, immunofluorescence, and real-time PCR, empowering your research in DNA repair, cell cycle regulation, and cancer biology.
• Adequate Quantity: With 100µg of antibody, you have sufficient material for multiple experiments, reducing the need for frequent restocking.
• Quality Assurance: Manufactured under stringent quality control measures to ensure the consistency and reliability of your results.
• Explore DNA Damage Response: Whether you're investigating GADD45GIP1's role in cellular stress responses, cell cycle checkpoints, or oncology, our Anti-GADD45GIP1 Antibody is your indispensable tool.

• Product Name

  GADD45GIP1 antibody

  Size

  100µg

  Form

  liquid

  Purification

  Immunogen affinity purified

  Purity

  ≥95% as determined by SDS-PAGE

  Host

  Rabbit

  Clonality

  polyclonal

  Isotype

  IgG

  Storage

  PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

  BACKGROUND

  Acts as a negative regulator of G1 to S cell cycle phase progression by inhibiting cyclin-dependent kinases. Inhibitory effects are additive with GADD45 proteins but occurs also in the absence of GADD45 proteins. Acts as a repressor of the orphan nuclear receptor NR4A1 by inhibiting AB domain-mediated transcriptional activity. May be involved in the hormone-mediated regulation of NR4A1 transcriptional activity. May play a role in mitochondrial protein synthesis.

  IMMUNOGEN INFORMATION

  Immunogen

  growth arrest and DNA-damage-inducible, gamma interacting protein 1

  Synonyms

  MRPL59, PLINP1, PRG6

  Observed MW

  25-28kd

  APPLICATION

  Tested Application

  ELISA, WB, IP

  Recommended Dilution

  WB: 1:500-1:2000; IP: 1:200-1:2000

  UNIPROT INFORMATION

  UniProt ID

  Q8TAE8

  IMAGES

   

  

  IP Result of anti-GADD45GIP1 (IP:FNab03296, 4ug; Detection:FNab03296 1:400) with mouse heart tissue lysate 4000ug.

  

  mouse heart tissue were subjected to SDS PAGE followed by western blot with FNab03296(GADD45GIP1 antibody) at dilution of 1:300