anti- GALC antibody

Embark on a comprehensive exploration of GALC (Galactocerebrosidase) and its critical role in myelin metabolism with our Anti-GALC Antibody, available in a set of four 100µg vials. GALC is a lysosomal enzyme essential for the breakdown of galactolipids in the nervous system, and its deficiency is associated with demyelinating diseases. This antibody is meticulously designed to specifically target GALC, allowing you to study its functions with precision.

Key Features:

• Precise Targeting: Rigorously validated to exclusively recognize GALC, reducing the risk of non-specific binding to other proteins.
• Economical Set: Receive four 100µg vials of the antibody, providing you with a cost-effective solution for multiple experiments.
• Versatile Applications: Suitable for various experimental techniques, including immunohistochemistry, enzyme assays, and immunoprecipitation, empowering your research in neurobiology and neurodegenerative diseases.
• Quality Assurance: Manufactured under stringent quality control measures to ensure the consistency and reliability of your results.
• Uncover Myelin Function: Whether you're investigating GALC's role in Krabbe disease, leukodystrophies, or central nervous system disorders, our Anti-GALC Antibody set is your trusted companion.

• Product Name

  GALC antibody

  Size

  100µg

  Form

  liquid

  Purification

  Immunogen affinity purified

  Purity

  ≥95% as determined by SDS-PAGE

  Host

  Rabbit

  Clonality

  polyclonal

  Isotype

  IgG

  Storage

  PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

  BACKGROUND

  Hydrolyzes the galactose ester bonds of galactosylceramide, galactosylsphingosine, lactosylceramide, and monogalactosyldiglyceride. Enzyme with very low activity responsible for the lysosomal catabolism of galactosylceramide, a major lipid in myelin, kidney and epithelial cells of small intestine and colon.

  IMMUNOGEN INFORMATION

  Immunogen

  galactosylceramidase

  Synonyms

  Galactocerebrosidase,galactosylceramidase, GALC, GALCERase

  Observed MW

  80 kDa, 30 kDa, 50 kDa

  APPLICATION

  Tested Application

  ELISA, WB, IHC

  Recommended Dilution

  WB: 1:500 - 1:2000; IHC: 1:20 - 1:200

  UNIPROT INFORMATION

  UniProt ID

  P54803

  IMAGES

   

  

  Immunohistochemistry of paraffin-embedded human gliomas using FNab03308(Galc antibody) at dilution of 1:50

  

  mouse brain tissue were subjected to SDS PAGE followed by western blot with FNab03308(Galc antibody) at dilution of 1:300