anti- GARS antibody

Dive into the intricate world of aminoacyl-tRNA synthetases and protein translation with our Anti-GARS Antibody. This indispensable research tool empowers you to investigate GARS-related studies. Key features include:

• High Specificity: Each 100µg vial contains antibodies meticulously designed to specifically target Glycyl-tRNA Synthetase (GARS), ensuring accuracy and reliability in your experiments.
• Enhanced Sensitivity: This antibody is highly sensitive, allowing for the precise detection of GARS in various experimental setups.
• Versatile Applications: Suitable for Western blotting, immunofluorescence, and immunohistochemistry, this antibody accommodates diverse research methodologies.
• Translation Insights: Gain valuable insights into GARS's role in aminoacylation of tRNAs, its significance in protein translation, and its implications in various cellular processes and diseases.

Empower your studies in molecular biology and protein synthesis with our Anti-GARS Antibody, your key to unraveling the complexities of aminoacyl-tRNA synthetases.

Product Name

GARS antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

BACKGROUND

This gene encodes glycyl-tRNA synthetase, one of the aminoacyl-tRNA synthetases that charge tRNAs with their cognate amino acids. The encoded enzyme is an (alpha)2 dimer which belongs to the class II family of tRNA synthetases. It has been shown to be a target of autoantibodies in the human autoimmune diseases, polymyositis or dermatomyositis. Two transcript variants encoding different isoforms have been found for this gene.

IMMUNOGEN INFORMATION

Immunogen

glycyl-tRNA synthetase

Synonyms

AP 4 A synthetase, CMT2D, DSMAV, GARS, Glycine tRNA ligase, glycyl tRNA synthetase, GlyRS, HMN5, SMAD1

Observed MW

70-83 kDa

APPLICATION

Tested Application

ELISA, WB, IHC

Recommended Dilution

WB: 1:500 - 1:2000; IHC: 1:50 - 1:200

UNIPROT INFORMATION

UniProt ID

P41250

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