anti- GATM antibody

Dive into the world of creatine biosynthesis and energy metabolism with our Anti-GATM Antibody. This vital research tool empowers you to investigate GATM-related studies. Key features include:

• High Specificity: Each 100µg vial contains antibodies meticulously designed to specifically target Glycine Amidinotransferase (GATM), ensuring accuracy and reliability in your experiments.
• Enhanced Sensitivity: This antibody is highly sensitive, ideal for detecting GATM in various experimental setups.
• Versatile Applications: Suitable for Western blotting, immunohistochemistry, and enzymatic assays, this antibody accommodates diverse research methodologies.
• Metabolic Insights: Gain valuable insights into GATM's role in creatine synthesis, its significance in energy production, and its implications in various neuromuscular and metabolic disorders.

Empower your studies in biochemistry and muscle physiology with our Anti-GATM Antibody, your key to understanding the intricacies of creatine metabolism.

Product Name

GATM antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

BACKGROUND

This gene encodes a mitochondrial enzyme that belongs to the amidinotransferase family. This enzyme is involved in creatine biosynthesis, whereby it catalyzes the transfer of a guanido group from L-arginine to glycine, resulting in guanidinoacetic acid, the immediate precursor of creatine. Mutations in this gene cause arginine:glycine amidinotransferase deficiency, an inborn error of creatine synthesis characterized by mental retardation, language impairment, and behavioral disorders.

IMMUNOGEN INFORMATION

Immunogen

glycine amidinotransferase (L-arginine:glycine amidinotransferase)

Synonyms

AGAT

Observed MW

43 kDa

APPLICATION

Tested Application

ELISA, WB, IHC, IF

Recommended Dilution

WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:200

UNIPROT INFORMATION

UniProt ID

P50440

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