anti- GCK antibody

Embark on a journey into glucose metabolism and insulin regulation with our Anti-GCK Antibody. This vital research tool empowers you to investigate GCK-related studies. Key features include:

• High Specificity: Each 100µg vial contains antibodies carefully designed to specifically target Glucokinase (GCK), ensuring accuracy and reliability in your experiments.
• Enhanced Sensitivity: This antibody is highly sensitive, ideal for detecting GCK in various experimental setups.
• Versatile Applications: Suitable for enzyme assays, immunohistochemistry, and diabetes research, this antibody adapts to a range of research methodologies.
• Metabolic Insights: Gain valuable insights into GCK's role in glucose homeostasis, its significance in insulin secretion, and its implications in various metabolic and endocrine disorders.

Elevate your studies in diabetes research and metabolic regulation with our Anti-GCK Antibody, your key to understanding the intricacies of glucose metabolism.

Product Name

GCK antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Catalyzes the initial step in utilization of glucose by the beta-cell and liver at physiological glucose concentration. Glucokinase has a high Km for glucose, and so it is effective only when glucose is abundant. The role of GCK is to provide G6P for the synthesis of glycogen. Pancreatic glucokinase plays an important role in modulating insulin secretion. Hepatic glucokinase helps to facilitate the uptake and conversion of glucose by acting as an insulin-sensitive determinant of hepatic glucose usage.

IMMUNOGEN INFORMATION

Immunogen

glucokinase(hexokinase 4)

Observed MW

50-52 kDa

APPLICATION

Tested Application

ELISA, WB

Recommended Dilution

WB: 1:500-1:2000

UNIPROT INFORMATION

UniProt ID

P35557

IMAGES

mouse liver tissue were subjected to SDS PAGE followed by western blot with FNab03384(GCK antibody) at dilution of 1:600