anti- GEMIN6 antibody

Uncover the intricate functions of Gem-associated Protein 6 (GEMIN6) in RNA processing and cellular biology with our Anti-GEMIN6 Antibody. This meticulously crafted research tool is designed to provide you with the precision and specificity essential for accurate results. Key features include:

• High Specificity: Our antibody is specifically engineered to target GEMIN6, ensuring accurate and reliable results in your research. It recognizes GEMIN6 with exceptional specificity, facilitating confident data interpretation.

• RNA Processing Insights: Gain valuable insights into GEMIN6's role in small nuclear ribonucleoprotein assembly (snRNP), its potential implications in mRNA splicing, and its significance in cellular RNA processing.

• Versatile Sizing: The 100µg size is ideal for multiple experiments while preserving product freshness and quality.

• Broad Applications: This antibody is suitable for various research methodologies, from studying RNA-related processes to exploring GEMIN6's interactions with other RNA-binding proteins.

Empower your research in the fields of RNA biology, cellular functions, and mRNA splicing as you delve into the role of GEMIN6 in RNA processing.

Product Name

GEMIN6 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

The SMN complex plays a catalyst role in the assembly of small nuclear ribonucleoproteins(snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs. Most spliceosomal snRNPs contain a common set of Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP. In the cytosol, the Sm proteins SNRPD1, SNRPD2, SNRPE, SNRPF and SNRPG are trapped in an inactive 6S pICln-Sm complex by the chaperone CLNS1A that controls the assembly of the core snRNP. Dissociation by the SMN complex of CLNS1A from the trapped Sm proteins and their transfer to an SMN-Sm complex triggers the assembly of core snRNPs and their transport to the nucleus.

IMMUNOGEN INFORMATION

Immunogen

gem(nuclear organelle) associated protein 6

Observed MW

19kd

APPLICATION

Tested Application

ELISA, WB

Recommended Dilution

WB: 1:500-1:2000

UNIPROT INFORMATION

UniProt ID

Q8WXD5

IMAGES

HEK-293 cells were subjected to SDS PAGE followed by western blot with FNab03421(GEMIN6 antibody) at dilution of 1:300