anti- GEMIN7 antibody

Embark on a journey of discovery as you explore the role of Gem-associated Protein 7 (GEMIN7) in RNA processing and cellular functions with our meticulously crafted Anti-GEMIN7 Antibody. This research tool is designed to provide you with the precision and specificity necessary for accurate results. Key features include:

• High Specificity: Our antibody is engineered for the specific targeting of GEMIN7, ensuring accurate and reliable results in your research. It recognizes GEMIN7 with exceptional specificity, facilitating data interpretation.

• RNA Processing Insights: Gain valuable insights into GEMIN7's involvement in small nuclear ribonucleoprotein assembly (snRNP), its potential implications in mRNA splicing, and its significance in cellular RNA processing.

• Versatile Sizing: The 100µg size is ideal for multiple experiments while maintaining product freshness and quality.

• Broad Applications: This antibody is suitable for various research methodologies, from investigating RNA-related processes to exploring GEMIN7's interactions with other RNA-binding proteins.

Advance your research in the fields of RNA biology, cellular functions, and mRNA splicing, as you delve into the role of GEMIN7 in RNA processing.

Product Name

GEMIN7 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

The SMN complex plays a catalyst role in the assembly of small nuclear ribonucleoproteins(snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs. Most spliceosomal snRNPs contain a common set of Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP. In the cytosol, the Sm proteins SNRPD1, SNRPD2, SNRPE, SNRPF and SNRPG are trapped in an inactive 6S pICln-Sm complex by the chaperone CLNS1A that controls the assembly of the core snRNP. Dissociation by the SMN complex of CLNS1A from the trapped Sm proteins and their transfer to an SMN-Sm complex triggers the assembly of core snRNPs and their transport to the nucleus.

IMMUNOGEN INFORMATION

Immunogen

gem(nuclear organelle) associated protein 7

APPLICATION

Tested Application

ELISA

UNIPROT INFORMATION

UniProt ID

Q9H840