anti- GHRL antibody

Dive into the world of the appetite-regulating hormone Ghrelin with our meticulously crafted Anti-GHRL Antibody. This research tool is designed to provide you with the precision and specificity necessary for accurate results. Key features include:

• High Specificity: Our antibody is specifically engineered to target Ghrelin, ensuring accurate and reliable results in your research. It recognizes Ghrelin with exceptional specificity, facilitating data interpretation.

• Appetite Research: Gain valuable insights into Ghrelin's role in appetite regulation, its significance in nutrition research, and its potential implications in metabolic and eating disorders.

• Versatile Sizing: The 100µg size is ideal for multiple experiments while ensuring product freshness and quality.

• Wide Applications: This antibody is suitable for various research methodologies, from studying appetite-related processes to exploring Ghrelin's interactions with other regulatory proteins.

Advance your research in the fields of endocrinology, nutrition, and metabolic disorders, unraveling the role of Ghrelin in appetite regulation.

Product Name

GHRL antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

BACKGROUND

This gene encodes the ghrelin-obestatin preproprotein that is cleaved to yield two peptides, ghrelin and obestatin. Ghrelin is a powerful appetite stimulant and plays an important role in energy homeostasis. Its secretion is initiated when the stomach is empty, whereupon it binds to the growth hormone secretagogue receptor in the hypothalamus which results in the secretion of growth hormone (somatotropin). Ghrelin is thought to regulate multiple activities, including hunger, reward perception via the mesolimbic pathway, gastric acid secretion, gastrointestinal motility, and pancreatic glucose-stimulated insulin secretion. It was initially proposed that obestatin plays an opposing role to ghrelin by promoting satiety and thus decreasing food intake, but this action is still debated. Recent reports suggest multiple metabolic roles for obestatin, including regulating adipocyte function and glucose metabolism. Alternative splicing results in multiple transcript variants. In addition, antisense transcripts for this gene have been identified and may potentially regulate ghrelin-obestatin preproprotein expression.

IMMUNOGEN INFORMATION

Immunogen

ghrelin/obestatin prepropeptide

Synonyms

MTLRP

Observed MW

15 kDa

APPLICATION

Tested Application

ELISA, WB, IHC

Recommended Dilution

WB: 1:500 - 1:2000; IHC: 1:50 - 1:200

UNIPROT INFORMATION

UniProt ID

Q9UBU3

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