anti- GLRX2 antibody

Delve into the intricate world of glutaredoxin 2 (GLRX2) and its crucial role in redox regulation and cellular research using our specialized Anti-GLRX2 Antibody. This antibody is characterized by several key features:

• Precision Targeting: Engineered to specifically recognize GLRX2, this antibody ensures the reliability and accuracy of your research findings.

• Cellular Insights: Investigate GLRX2's essential function in redox processes, revealing its implications in cellular homeostasis, oxidative stress responses, and potential relevance to health and disease.

• Optimal Quantity: With 100µg of reagent, you have ample material for multiple experiments while preserving product quality and performance.

• Versatile Applications: Whether you're exploring redox regulation, oxidative stress, or GLRX2's interactions with other cellular components, this antibody is adaptable to various research methodologies.

Empower your redox and cellular research as you decipher the intricacies of GLRX2.

Product Name

GLRX2 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Glutathione-dependent oxidoreductase that facilitates the maintenance of mitochondrial redox homeostasis upon induction of apoptosis by oxidative stress. Involved in response to hydrogen peroxide and regulation of apoptosis caused by oxidative stress. Acts as a very efficient catalyst of monothiol reactions because of its high affinity for protein glutathione-mixed disulfides. Can receive electrons not only from glutathione(GSH), but also from thioredoxin reductase supporting both monothiol and dithiol reactions. Efficiently catalyzes both glutathionylation and deglutathionylation of mitochondrial complex I, which in turn regulates the superoxide production by the complex. Overexpression decreases the susceptibility to apoptosis and prevents loss of cardiolipin and cytochrome c release.

IMMUNOGEN INFORMATION

Immunogen

glutaredoxin 2

Synonyms

GRX2

Observed MW

16 kDa

APPLICATION

Tested Application

ELISA, WB

Recommended Dilution

WB: 1:500-1:2000

UNIPROT INFORMATION

UniProt ID

Q9NS18

IMAGES

A549 cells were subjected to SDS PAGE followed by western blot with FNab03491(GLRX2 antibody) at dilution of 1:200