anti- GLUD1 antibody

Uncover the mysteries of glutamate dehydrogenase 1 (GLUD1) and its essential role in cellular metabolism and neurological research using our specialized Anti-GLUD1 Antibody. This antibody is defined by several key features:

• Precision Targeting: Engineered for specific recognition of GLUD1, this antibody ensures accurate and reliable results in your research, providing the precision you need.

• Cellular Insights: Investigate GLUD1's pivotal role in glutamate metabolism, energy production, and its potential implications in neurological disorders and metabolic research.

• Ideal Quantity: The 100µg size offers an ample amount of reagent for multiple experiments, maintaining the freshness and quality of your product.

• Versatile Applications: Whether you're exploring glutamate metabolism, mitochondrial function, or GLUD1's interactions with other cellular components, this antibody is adaptable to various research methodologies.

Elevate your cellular and metabolic research as you decipher the intricacies of GLUD1.

Product Name

GLUD1 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

BACKGROUND

This gene encodes glutamate dehydrogenase, which is a mitochondrial matrix enzyme that catalyzes the oxidative deamination of glutamate to alpha-ketoglutarate and ammonia. This enzyme has an important role in regulating amino acid-induced insulin secretion. It is allosterically activated by ADP and inhibited by GTP and ATP. Activating mutations in this gene are a common cause of congenital hyperinsulinism. Alternative splicing of this gene results in multiple transcript variants. The related glutamate dehydrogenase 2 gene on the human X-chromosome originated from this gene via retrotransposition and encodes a soluble form of glutamate dehydrogenase. Related pseudogenes have been identified on chromosomes 10, 18 and X.

IMMUNOGEN INFORMATION

Immunogen

glutamate dehydrogenase 1

Synonyms

GLUD

Observed MW

50 kDa

APPLICATION

Tested Application

ELISA, WB, IHC

Recommended Dilution

WB: 1:500 - 1:2000; IHC: 1:100 - 1:200

UNIPROT INFORMATION

UniProt ID

P00367

IMAGES

Immunohistochemistry of paraffin-embedded human esophagus using FNab03498(GLUD1 antibody) at dilution of 1:100

HeLa cells were subjected to SDS PAGE followed by western blot with FNab03498(GLUD1 antibody) at dilution of 1:1000