anti- GM2A antibody

anti- GM2A antibody

Product Name

GM2A antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

The large binding pocket can accommodate several single chain phospholipids and fatty acids, GM2A also exhibits some calcium-independent phospholipase activity(By similarity). Binds gangliosides and stimulates ganglioside GM2 degradation. It stimulates only the breakdown of ganglioside GM2 and glycolipid GA2 by beta-hexosaminidase A. It extracts single GM2 molecules from membranes and presents them in soluble form to beta-hexosaminidase A for cleavage of N-acetyl-D-galactosamine and conversion to GM3.

IMMUNOGEN INFORMATION

Immunogen

GM2 ganglioside activator

Observed MW

22 kDa

APPLICATION

Tested Application

ELISA, IHC, WB, IP

Recommended Dilution

WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200

UNIPROT INFORMATION

UniProt ID

P17900

IMAGES

Immunohistochemistry of paraffin-embedded human colon cancer using FNab03517(GM2A antibody) at dilution of 1:100

IP Result of anti-GM2A (IP:FNab03517, 3ug; Detection:FNab03517 1:600) with HEK-293 cells lysate 2800ug.

rat kidney tissue were subjected to SDS PAGE followed by western blot with FNab03517(GM2A Antibody) at dilution of 1:300