anti- GM2A antibody

anti- GM2A antibody

Product Name

GM2A antibody

Size

100µg

Form

liquid

Purification

Protein A+G purification

Purity

≥95% as determined by SDS-PAGE

Host

Mouse

Clonality

monoclonal

Isotype

IgG2a

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

The large binding pocket can accommodate several single chain phospholipids and fatty acids, GM2A also exhibits some calcium-independent phospholipase activity(By similarity). Binds gangliosides and stimulates ganglioside GM2 degradation. It stimulates only the breakdown of ganglioside GM2 and glycolipid GA2 by beta-hexosaminidase A. It extracts single GM2 molecules from membranes and presents them in soluble form to beta-hexosaminidase A for cleavage of N-acetyl-D-galactosamine and conversion to GM3.

IMMUNOGEN INFORMATION

Immunogen

GM2 ganglioside activator

Synonyms

Ganglioside GM2 activator, GM2 AP, GM2 ganglioside activator, GM2A, SAP 3

Observed MW

22 kDa

APPLICATION

Tested Application

ELISA, WB

Recommended Dilution

WB: 1:500-1:1000

UNIPROT INFORMATION

UniProt ID

P17900

IMAGES

Hela cells were subjected to SDS PAGE followed by western blot with FNab03518(GM2A Antibody) at dilution of 1:500