anti- GOT1 antibody

anti- GOT1 antibody

Product Name

GOT1 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Biosynthesis of L-glutamate from L-aspartate or L-cysteine. Important regulator of levels of glutamate, the major excitatory neurotransmitter of the vertebrate central nervous system. Acts as a scavenger of glutamate in brain neuroprotection. The aspartate aminotransferase activity is involved in hepatic glucose synthesis during development and in adipocyte glyceroneogenesis. Using L-cysteine as substrate, regulates levels of mercaptopyruvate, an important source of hydrogen sulfide. Mercaptopyruvate is converted into H(2)S via the action of 3-mercaptopyruvate sulfurtransferase(3MST). Hydrogen sulfide is an important synaptic modulator and neuroprotectant in the brain.

IMMUNOGEN INFORMATION

Immunogen

glutamic-oxaloacetic transaminase 1, soluble(aspartate aminotransferase 1)

Synonyms

AATC, CAT, GIG18, GOT1, Transaminase A

Observed MW

43-46 kDa

APPLICATION

Tested Application

ELISA, WB, IP

Recommended Dilution

WB: 1:500-1:2000; IP: 1:500-1:2000

UNIPROT INFORMATION

UniProt ID

P17174

IMAGES

IP Result of anti-GOT1 (IP: FNab03567, 4ug; Detection: FNab03567 1:1000) with mouse brain tissue lysate 3600ug.

HepG2 cells were subjected to SDS PAGE followed by western blot with FNab03567( GOT1 Antibody) at dilution of 1:1000