anti- GPT antibody

anti- GPT antibody

Product Name

GPT antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

BACKGROUND

This gene encodes cytosolic alanine aminotransaminase 1 (ALT1); also known as glutamate-pyruvate transaminase 1. This enzyme catalyzes the reversible transamination between alanine and 2-oxoglutarate to generate pyruvate and glutamate and, therefore, plays a key role in the intermediary metabolism of glucose and amino acids. Serum activity levels of this enzyme are routinely used as a biomarker of liver injury caused by drug toxicity, infection, alcohol, and steatosis. A related gene on chromosome 16 encodes a putative mitochondrial alanine aminotransaminase.

IMMUNOGEN INFORMATION

Immunogen

glutamic-pyruvate transaminase (alanine aminotransferase)

Synonyms

AAT1, GPT1

Observed MW

50 kDa

APPLICATION

Tested Application

ELISA, WB, IHC

Recommended Dilution

WB: 1:200 - 1:1000; IHC: 1:50 - 1:100

UNIPROT INFORMATION

UniProt ID

P24298

IMAGES

Immunohistochemistry of paraffin-embedded human stomach using FNab03619(GPT antibody) at dilution of 1:50

mouse lung tissue were subjected to SDS PAGE followed by western blot with FNab03619(GPT antibody) at dilution of 1:1000