anti- GRB2 antibody

anti- GRB2 antibody

Product Name

GRB2 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

BACKGROUND

The protein encoded by this gene binds the epidermal growth factor receptor and contains one SH2 domain and two SH3 domains. Its two SH3 domains direct complex formation with proline-rich regions of other proteins, and its SH2 domain binds tyrosine phosphorylated sequences. This gene is similar to the Sem5 gene of C.elegans, which is involved in the signal transduction pathway. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene.

IMMUNOGEN INFORMATION

Immunogen

growth factor receptor-bound protein 2

Synonyms

ASH

Observed MW

33 kDa

APPLICATION

Tested Application

ELISA, WB, IF, IHC

Recommended Dilution

WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:10 - 1:100

UNIPROT INFORMATION

UniProt ID

P62993

IMAGES

Immunohistochemistry of paraffin-embedded mouse kidney using FNab03642(GRB2 antibody) at dilution of 1:100

SW480 cells were subjected to SDS PAGE followed by western blot with FNab03642(GRB2 Antibody) at dilution of 1:1000