anti- GSPT2 antibody

anti- GSPT2 antibody

Product Name

GSPT2 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Involved in translation termination in response to the termination codons UAA, UAG and UGA. May play a role as a potent stimulator of the release factor activity of ETF1. Exhibits GTPase activity, which is ribosome-and ETF1-dependent. May play a role in cell cycle progression. Component of the transient SURF complex which recruits UPF1 to stalled ribosomes in the context of nonsense-mediated decay(NMD) of mRNAs containing premature stop codons.

IMMUNOGEN INFORMATION

Immunogen

G1 to S phase transition 2

Synonyms

ERF3B

Observed MW

69 kDa

APPLICATION

Tested Application

ELISA, WB, IHC

Recommended Dilution

WB: 1:500-1:2000; IHC: 1:20-1:200

UNIPROT INFORMATION

UniProt ID

Q8IYD1

IMAGES

Immunohistochemistry of paraffin-embedded human colon cancer using FNab03681(GSPT2 antibody) at dilution of 1:100

MCF7 cells were subjected to SDS PAGE followed by western blot with FNab03681(GSPT2 antibody) at dilution of 1:500