anti- HDAC1 antibody

anti- HDAC1 antibody

Product Name

HDAC1 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

BACKGROUND

Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2, it deacetylates p53 and modulates its effect on cell growth and apoptosis.

IMMUNOGEN INFORMATION

Immunogen

histone deacetylase 1

Synonyms

DKFZp686H12203, GON 10, HD1, HDAC1, histone deacetylase 1, RPD3, RPD3L1

Observed MW

60 kDa

APPLICATION

Tested Application

ELISA, WB, IHC, IF

Recommended Dilution

WB: 1:500 - 1:2000; IHC: 1:100 - 1:200; IF: 1:50 - 1:100

UNIPROT INFORMATION

UniProt ID

Q13547

IMAGES

Immunohistochemistry of paraffin-embedded human prostate cancer using FNab03792(HDAC1 antibody) at dilution of 1:100

Immunofluorescence analysis of A549 cells using FNab03792 (HDAC1 antibody). Blue: DAPI for nuclear staining.

HepG2 cells were subjected to SDS PAGE followed by western blot with FNab03792(HDAC1 antibody) at dilution of 1:1000