anti- Hemoglobin alpha antibody

anti- Hemoglobin alpha antibody

Product Name

Hemoglobin alpha antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

BACKGROUND

The human alpha globin gene cluster located on chromosome 16 spans about 30 kb and includes seven loci: 5'- zeta - pseudozeta - mu - pseudoalpha-1 - alpha-2 - alpha-1 - theta - 3'. The alpha-2 (HBA2) and alpha-1 (HBA1) coding sequences are identical. These genes differ slightly over the 5' untranslated regions and the introns, but they differ significantly over the 3' untranslated regions. Two alpha chains plus two beta chains constitute HbA, which in normal adult life comprises about 97% of the total hemoglobin; alpha chains combine with delta chains to constitute HbA-2, which with HbF (fetal hemoglobin) makes up the remaining 3% of adult hemoglobin. Alpha thalassemias result from deletions of each of the alpha genes as well as deletions of both HBA2 and HBA1; some nondeletion alpha thalassemias have also been reported.

IMMUNOGEN INFORMATION

Immunogen

hemoglobin, alpha 1

Synonyms

Alpha globin, HBA1, HBA2, Hemoglobin a, Hemoglobin alpha chain, Hemoglobin subunit alpha, hemoglobin, alpha 1

Observed MW

13 kDa

APPLICATION

Tested Application

ELISA, WB, IHC

Recommended Dilution

WB: 1:500 - 1:2000; IHC: 1:50 - 1:100

UNIPROT INFORMATION

UniProt ID

P69905

IMAGES

Immunohistochemistry of paraffin-embedded mouse heart using FNab03825(Hemoglobin alpha antibody) at dilution of 1:100

mouse liver were subjected to SDS PAGE followed by western blot with FNab03825(Hemoglobin alpha antibody) at dilution of 1:1000