anti- HIST2H2AA4 antibody

anti- HIST2H2AA4 antibody

Product Name

HIST2H2AA4 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

IMMUNOGEN INFORMATION

Immunogen

histone cluster 2, H2aa4

Synonyms

H2AFO, HIST2H2AA

Observed MW

14 kDa

APPLICATION

Tested Application

ELISA, IHC, WB

Recommended Dilution

WB: 1:500-1:2000; IHC: 1:20-1:200

UNIPROT INFORMATION

UniProt ID

Q6FI13

IMAGES

Immunohistochemistry of paraffin-embedded human liver cancer tissue slide using FNab03879(HIST2H2AA4 Antibody) at dilution of 1:50

L02 cells were subjected to SDS PAGE followed by western blot with FNab03879(HIST2H2AA4 Antibody) at dilution of 1:600