anti- HNMT antibody

anti- HNMT antibody

Product Name

HNMT antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

BACKGROUND

In mammals, histamine is metabolized by two major pathways: N(tau)-methylation via histamine N-methyltransferase and oxidative deamination via diamine oxidase. This gene encodes the first enzyme which is found in the cytosol and uses S-adenosyl-L-methionine as the methyl donor. In the mammalian brain, the neurotransmitter activity of histamine is controlled by N(tau)-methylation as diamine oxidase is not found in the central nervous system. A common genetic polymorphism affects the activity levels of this gene product in red blood cells. Multiple alternatively spliced transcript variants that encode different proteins have been found for this gene.

IMMUNOGEN INFORMATION

Immunogen

histamine N-methyltransferase

Synonyms

HMT

Observed MW

27 kDa

APPLICATION

Tested Application

ELISA, WB, IHC, IP

Recommended Dilution

WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IP : 1:20 - 1:50

UNIPROT INFORMATION

UniProt ID

P50135

IMAGES

Immunohistochemistry of paraffin-embedded mouse heart using FNab03944(HNMT antibody) at dilution of 1:50

human liver tissue were subjected to SDS PAGE followed by western blot with FNab03944(HNMT antibody) at dilution of 1:1000