anti- HOOK3 antibody

anti- HOOK3 antibody

Product Name

HOOK3 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Probably serves as a target for the spiC protein from Salmonella typhimurium, which inactivates it, leading to a strong alteration in cellular trafficking(By similarity). Component of the FTS/Hook/FHIP complex(FHF complex). The FHF complex may function to promote vesicle trafficking and/or fusion via the homotypic vesicular protein sorting complex(the HOPS complex). May regulate clearance of endocytosed receptors such as MSR1. Participates in defining the architecture and localization of the Golgi complex.

IMMUNOGEN INFORMATION

Immunogen

hook homolog 3(Drosophila)

Observed MW

83 kDa

APPLICATION

Tested Application

ELISA, WB, IHC, IF, IP

Recommended Dilution

WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200; IF: 1:20-1:200

UNIPROT INFORMATION

UniProt ID

Q86VS8

IMAGES

Immunohistochemistry of paraffin-embedded human kidney using FNab03968(HOOK3 antibody) at dilution of 1:100

IP Result of anti-HOOK3 (IP:FNab03968, 4ug; Detection:FNab03968 1:500) with mouse kidney tissue lysate 4000ug.

human liver tissue were subjected to SDS PAGE followed by western blot with FNab03968(HOOK3 antibody) at dilution of 1:500